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They are found in three isoforms and amongst them SOD1 (Cu/Zn-SOD), a predominant oxygen radical scavenger, is localized in the cytoplasm, mitochondrial intermembrane space, nucleus, and lysosomes, whereas SOD2 (Mn-SOD) and SOD3 (Cu/Zn-SOD) are localized in the mitochondrion and extracellular matrix respectively [81, 82]
Ho KY, Veldhuis JD, Johnson ML, Furlanetto R, Evans WS, Alberti K, et al
10.1016/j.jmig.2006.07.013 26 DengX.SzaboS.KhomenkoT.TolstanovaG.PaunovicB.FrenchS
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