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These should definetely be approved for T1s The resistance to using GLP-1 RAs in type 1 diabetes can no longer be justified as a simple lack of indication. Studies such as Viral Shah et al
They often contain herbal blends or other "support" ingredients that are not the same as prescription semaglutide or tirzepatide, and they are not evaluated by the FDA for weight-management efficacy
For all of these questions, the answer is no. Oral semaglutide (Wegovy pill, Ozempic pill, or Rybelsus) must be taken on an empty stomach
FDA approval dates for these GLP-1 RAs are detailed in Table S3
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