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Eur J Nutr 2016;55:4553

It supports a healthy skin barrier

Because GLP-1 agonists independently reduce hepatic lipogenesis and improve insulin sensitivity, which overlaps mechanistically with the lipotropic pathway

The researchers assessed the change in body weight from baseline within each trial and subgroup and they also carried out a mediation analysis to differentiate between direct and indirect effects of semaglutide on weight loss, the latter of which was mediated by nausea or vomiting