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The resultant endothelial activation can lead to endothelial cell dysfunction (ECD)
Key mechanisms include the relief of hypothalamic-pituitary-ovarian (HPO) axis inhibition through weight loss and improved insulin sensitivity, alongside improved endometrial receptivity driven by increased SHBG and decreased free androgens (83, 167, 168)
Although GLP-1RAs have shown remarkable efficacy in weight management, several barriers limit their full integration into mainstream obesity care
Why Is Natural GLP-1 Activation Important
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