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It contains small amounts of monacolin K, which is the active ingredient in the statin drug Lovastatin ( According to a review of 15 randomized clinical trials, red yeast rice was found more effective than a statin in lowering triglycerides and comparable in lowering LDL (bad) cholesterol and elevating HDL (good) cholesterol, though it was less effective in lowering total cholesterol count ( Whats more, in an older study in 5,000 people in China who had experienced heart attacks, red yeast rice reduced the risk of subsequent heart attacks by 45% and the risk of dying during the study period by 33% ( Still, the amount of the active ingredient in supplements can vary up to 100-fold depending on the brand ( Due to the potency of monacolin K, the Food and Drug Administration (FDA) has ruled that red yeast rice products containing this substance should be considered a drug rather than a supplement ( Some manufacturers try to evade these regulations by selling red yeast rice supplements that only contain trace amounts of monacolin K

In the UK, GLP-1 medications for weight management (such as Wegovy) are typically initiated within specialist weight management services according to NICE criteria

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Real world data show that most people regain all of the weight lost within 2 years of stopping the medication