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Semaglutide improved BCL-2 signaling and reduced BAX signaling in the MPTP mouse model of PD [156, 157]
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While vitamin B6 is generally regarded as a safe and essential nutrient, excessive intake, especially doses exceeding 200 mg per day over several months, can lead to sensory neuropathy
Adequate hydration (aim for at least 64 ounces of water daily) and fiber supplementation are first-line management strategies
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