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Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30
Type 2 diabetes mellitus (T2DM) is increasingly prevalent worldwide and is associated with abdominal obesity in genetically susceptible individuals
Use sterile, pre-cooled vials to minimize freeze-thaw cycles
GLP-1 receptor agonists such as exenatide, liraglutide, semaglutide, and tirzepatide provide glucose-dependent insulin stimulation, weight reduction, and cardiovascular benefits
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