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Altasciences Preclinical Approaches to GLP-1 RA Development Preclinical studies for first generation GLP-1 RA therapeutics for treatment of diabetes have generally been standard GLP studies, conducted with normal-weight animal models
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The GLP-1 appetite suppression mechanism works by signaling the brains satiety centers to reduce hunger and increase feelings of fullness
Acknowledgements This project was supported by the National Natural Science Foundation of China (82272232, 82170775, 82370765, 82270802, 82100806, and 82300766) and the Open Project of Hubei Key Laboratory (2023KFZZ009)
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