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Two options with genuine clinical support: Retinaldehyde (retinal) sits one step closer to retinoic acid than retinol, so it converts more efficiently with less irritation than standard retinol

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Seek immediate medical attention for signs of severe dehydration, diabetic ketoacidosis, or severe flank pain with fever

Other side effects include: Since these drugs are administered via injection, reactions like itching, redness, swelling or a small lump at the injection site may occur