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Different people may respond differently to these medications, and the same person may even feel different depending on dose changes, appetite, stomach symptoms, or what they ate that day
Future large long-term RCTs with primary or secondary outcomes, including thyroid disorders and real-world data, are needed to elucidate the association between GLP-1 receptor agonists and the risk of various thyroid disorders, particularly thyroid cancer
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(A head-to-head trial of the two medications, funded by Eli Lilly, found that patients on Zepbound lost an average of 20 percent of their weight, versus about 14 percent for those on Wegovy.) Nevertheless, its much harder to get Zepbound than Wegovy
