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2009;339:b2535
How does tirzepatide's weight loss performance compare to earlier GLP-1 medications that have been on the market longer
Mutations in genes that regulate the cell cycle and DNA repair further suggested mechanisms of increased CNAs: a truncating insertion in FGFR1OP, which anchors microtubules 47 (patient CAS-D) and deleterious missense mutations in WRN, associated with homology-directed repair and stability of fragile sites 48 , in patients CAS-C, CAS-F and MI-F
Severe gastroparesis or other serious gastrointestinal disorders, because tirzepatide slows stomach emptying, which can aggravate these conditions
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