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A clear demonstration was obtained that BPC 157 stimulated both the egr-1 gene (critical in proliferation, differentiation, and inflammation during cholestatic liver injury, cytokine and growth factor generation, and early extracellular matrix (collagen) formation) (Zhang et al., 2011) and its co-repressor gene nab2 (Seveljevic-Jaran et al., 2006
BPC-157 TB-500 Side Effects & Safety BPC-157 Generally very well tolerated in research models Minimal reported side effects at standard doses No significant hormonal impact Theoretical concern: may promote angiogenesis in existing tumors (same as any pro-angiogenic compound) TB-500 Well tolerated
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