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et al., Selective and membrane-permeable small-molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice, Biochem Pharmacol, 2018

BPH affects the quality of life of about 40% of men in their fifth decade and 90% of men in their ninth decade.[2]It is unusual before the age of 45 and affects men of Afro-American origin more severely than white men, possibly due to higher testosterone levels, 5-alpha-reductase activity, androgen receptor expression and growth factor activity

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