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GLP-1 receptor agonists like semaglutide, liraglutide, and dulaglutide work by mimicking natural hormones that regulate blood glucose and appetite, but individual responses vary considerably
For the cerebrovascular uptake study ( n = 22), male and female homozygous APOE2-, APOE3-, and APOE4-TR mice were euthanized at 26-weeks (Supplementary Table S2)
1991;49(23):L189-94
The mechanism isnt fully understood (possibly due to direct effect on SA node or indirect via autonomic changes from weight loss or nausea)
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