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Tseng et al., 2025)
Although there is ongoing debate regarding whether SCFAs can promote the differentiation of peripheral CD4 + T cells into forkhead box P3 + (Foxp3 + ) T cells, it is generally accepted that SCFAs can enhance the function of Treg cells either through GPR43 activation or by influencing histone acetylation levels
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Kakavand H, Crainic O, Lum T, O'Toole SA, Kefford RF, Thompson JF et al
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