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A small RCT (n=21) found that inhaled glutathione (600 mg twice daily for 3 months) modestly improved some pulmonary function parameters (Griese et al., Am J Respir Crit Care Med, 2004) [47]
Besides exercise and nutrition, the paper also highlights weight loss, caloric restriction, and metabolic flexibility as key strategies to reduce oxidative load and improve glutathione recycling
Although only certain isomers of -tocopherol are retained in the circulation, all forms are absorbed and metabolized by the liver
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