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Patients with pernicious anemia This autoimmune condition destroys intrinsic factor, the protein required for B12 absorption in the small intestine

Abbreviations CIN: Contrast-induced nephropathy LC: L-carnitine URO: Urographin TOS: Total oxidans status TAS: Total antioxidant status OSI: Oxidative stress index TNF-: Tumor necrosis factor alpha Cas-3: Caspase-3 Bcl-2: B-cell lymphoma 2 Bax: Bcl-2-associated X protein Cas-9: Caspase-9 ROS: Reactive oxygen species cDNA: Complementary DNA qPCR: Real-time quantitative polymerase chain reaction NF-B: Nuclear factor kappa-light-chain-enhancer of activated B cells HMGB1: High mobility group box 1 protein TLR4: Toll Like Receptor 4 SIRT-1: Sirtuin 1 References Nath KA, Norby SM (2000) Reactive oxygen species and acute renal failure

Neufeld et al., 2011

Rossi, S