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Approximately 15% of couples worldwide experience infertility, and 2.5%12% of men of reproductive age are estimated to be infertile, with marked regional variations (Levine et al., 2023)
Epigenetic modifications Epigenetic changes, including Nrf2 promoter hypermethylation ( 50% reduction in expression), diminish antioxidant defense and GSH synthesis [57]
They are formed in the body from normal metabolism (such as converting food to energy) but are increased by exposure to environmental toxins, such as cigarette smoke and air pollution
Understanding Glutathione Glutathione is a naturally occurring antioxidant found in every cell of the body
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