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Figure 1 4 Overview of the GLP-1 mechanism GLP-1 is an incretin hormone composed of 3031 amino acids, produced by post-translational processing of proglucagon and secreted by intestinal L-cells in response to nutritional and inflammatory stimuli, as well as by neurons in the brainstem

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If you discontinue the medication without establishing permanent dietary and lifestyle changes, hunger signals will gradually return to baseline, which can lead to regaining lost weight