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By acting at the genetic level, Epitalon offers the possibility of realigning the entire circadian system rather than simply adding more melatonin to a broken clock

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This mechanism is likely due to the C-terminal domain of NCOA4 binding to the conserved surface arginine (R23) of FTH1 in phagocytic cells, subsequently facilitating its interaction with autophagosomes and autolysosomes (14)