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Surprisingly, l-carnitine and acetylcarnitine, but not propionylcarnitine or butyrylcarnitine, rescued the sensitivity to DNA-damaging agents in combination with IDH1 inhibition, glutamine starvation, TMLHE knockdown, carnitine synthesis inhibition or succinate supplementation (Supplementary Fig
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it is essentially "spent." Oxidized glutathione (GSSG) occurs when two spent glutathione molecules bind together for stability
Each vial is securely packaged to maintain peptide integrity during transit and storage
