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The double-blind, randomized, placebo-controlled study enrolled 338 adults with obesity or overweight and related health conditions to assess the drugs efficacy, side effects, and safety
Plant Stress 5 :100105
For example, GH could stimulate ERK and Akt phosphorylation and inhibit apoptosis in cultures of osteoblasts lacking IGF-IR expression, but fail to induce cell proliferation in the same cultures (70)
This response was caused primarily by GH hypersecretion, as expression of a GH antagonist resulted in improvement of glucose homeostasis [129, 229]
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