The same goes for those experiencing excessive or persistent rectal bleeding and conditions like anal stenosis, anal stricture, or scar tissue formation
For this reason, individuals with a history of gout or elevated uric acid should be monitored carefully when initiating significant weight loss, whether through medication, diet, or surgery
KEY TAKEAWAYS Insulin resistance can be tested through fasting insulin and glucose ratios, even in countries where insulin testing is less common Rapid weight loss rates above 15% annually may indicate no need for dose increases Severe GI side effects warrant investigation beyond medication adjustment, including gallbladder evaluation DEXA scans provide valuable visceral fat measurements, but results should be interpreted alongside overall health markers Maintenance strategies should focus on nutritional stability before considering medication tapering NOTABLE QUOTE "It's not that the medicine causes the rebound weight gain, it's that with the medication in there, the body is getting better signals, and then you go and take the medication away and you're in the same boat." Dr
There's now some upside in HIMS even without GLP-1 growth, but I believe that caution is warranted for now