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Animal data suggests NSAIDs may blunt some of the healing signals that BPC-157 is proposed to potentiate, specifically COX-2-mediated prostaglandin pathways that contribute to tissue remodeling
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Although almost all tissues in the body have some ability to metabolize chemicals, smooth endoplasmic reticulum in the liver is the principal "metabolic clearing house" for both endogenous chemicals (e.g., cholesterol, steroid hormones, fatty acids, proteins) and exogenous substances (e.g., drugs, alcohol)
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