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In contrast, RAMP1/3 KO mice exhibited disrupted metabolic responses: Cagrilintide treatment increased relative fat mass and decreased lean mass, along with elevated leptin and insulin levels

Developing potential therapies that can be administered less frequently could benefit societies as well as individual patients, and it is a clear focus area for Novo Nordisk, commented Brian Vandahl, Senior Vice President of Global Research Technologies at Novo Nordisk

Approximately 7-8 days, supporting once-weekly research administration

Even the lowest maintenance dose of 5 mg produced meaningful results, averaging around 15% body weight reduction