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Its main functions are to maintain the pH of a product and neutralize metal ions
While glycolysis is the primary source of ATP in these cells, the PPP provides an alternative route for glucose metabolism, especially under conditions where glycolytic flux is altered, such as during immune activation or in hypoxic environments (De Santa et al., 2019
These studies indicate that for many patients, this treatment may safely delay the need for chronic dialysis therapy (53), may safely allow time for a PD access or a hemodialysis vascular access to mature without, for example, resorting to tunnel catheters (54), or may allow for a lower dose of dialysis treatment, at least as long as some residual kidney function is preserved (55)
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