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For example: Fatigue, unexplained weight loss, or abdominal pain may indicate liver disease or cancer Easy bruising, night sweats, or feeling full quickly (early satiety) may suggest a myeloproliferative disorder Swelling in the legs, reduced urine output, or persistent nausea may point to kidney disease In cases of very high B12 from injections (not oral supplements), some people have reported headache, nausea, diarrhea, facial flushing, or skin rash

Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests

Other Treatment Options for Portal Hypertension If endoscopic therapy, drug therapy, and/or dietary changes don't successfully control variceal bleeding or ascites (a buildup of fluid in your belly), you may require one of the following procedures to reduce the pressure in these veins