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Some drugs that can interact with cyclobenzaprine include sedatives such as: Benzodiazepines Monoamine oxidase inhibitors (MAOIs) Antidepressants Certain pain medications It is also important to note that cyclobenzaprine may interact with alcohol and other substances that cause drowsiness, so it should be avoided while taking this medication
This comorbidity is attributed to various factors, including the psychological impact of managing a chronic illness, potential shared genetic susceptibility, and common pathophysiological abnormalities, such as the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, and inflammatory state [9,10,11]
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