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18 A hallmark of MDR is the dysregulation of intracellular drug availability, primarily through impaired drug uptake and enhanced drug efflux, involving the SLC and ABC transporter families
Orlistat has important drug interactions, including with ciclosporin (avoid or monitor closely if unavoidable), warfarin (monitor INR), levothyroxine (separate by at least 4 hours and monitor TSH), antiepileptics (monitor for changes in seizure frequency), and acarbose (avoid combination)
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Did you know that the average ingredient expense for mixed medications rose from $308.49 to $710.36, indicating a 130.3% rise from 2012 to 2013
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