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Semaglutide is not contraindicated in patients with liver disease, and the FDA prescribing information does not list hepatic impairment as an absolute contraindication to its use

Discuss this pattern with your prescriber

The suppression of appetite caused by a GLP-1 RA will likely lead you to eat less overall, and to reach for unhealthy foods less frequently

There was a significant 24% reduction in the composite primary outcome in the semaglutide group compared with those taking placebo, with first events occurring in 5.8 versus 7.5 people per 100 person-years of follow-up, such that 20 people would need to be treated for 3 years to prevent one primary event