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ACT 2: Tirzepatide (Mounjaro & Zepbound) More Flexibility, Same Discipline Tirzepatide is a dual GIP/GLP-1 receptor agonist, making it pharmacologically distinct from semaglutide
A previous study reported that GLP-1Rs are observed in brain regions related to energy balance and regulation of moods, such as the amygdala, hippocampus, and dorsal raphe nucleus (Merchenthaler et al., 1999)
They should also help patients recognize when it may be time to talk to their prescriber about stepping up to pharmacologic treatment
Research has uncovered associations between healthy eating patterns, including higher dietary levels of vitamin B12, and a low incidence of depression
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