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But at the time, I hadn't yet fully embraced a weight-neutral approach to caring for my patients and caring for myself

For obesity therapeutics, Phase 3 trials are especially important because regulators want to see: Long-term weight loss sustainability Cardiovascular safety Real-world tolerability Effects on obesity-related conditions such as diabetes, sleep apnea, and osteoarthritis Retatrutides Phase 3 program, called TRIUMPH , includes multiple large-scale studies across different patient populations

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Changes in cytokine secretion profiles may affect the regulation of immune responses, inflammation, and immune cell communication (85)