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Therefore, theres a need for oral treatment options with weight-reduction efficacy similar to that of the approved and currently available injectable GLP-1 receptor agonists. Promising phase-two trials suggest orforglipron could help meet this need
| Sustained weight maintenance data | Limited | Yes (STEP 5, 104 weeks) | Tesofensine produces faster weight loss on a per-month basis, while semaglutide produces greater total weight loss over a longer treatment period and has demonstrated sustained results with continued use
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Keeping Track With Your Doctor Regular check-ups with your doctor are crucial during the transition from Wegovy to Zepbound
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