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It targets adipose tissue, stimulating the breakdown of stored fat (lipolysis) and preventing the formation of new fat (lipogenesis) within adipocytes

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2020;17:e1003198

The discovery of new lipolytic enzymes and coregulators, the demonstration that lipophagy and lysosomal lipolysis contribute to the degradation of cellular lipid stores and the characterization of numerous factors and signalling pathways that regulate lipid hydrolysis on transcriptional and post-transcriptional levels have revolutionized our understanding of lipolysis