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2020b;30:32938
In addition, the authors noted that tirzepatide showed no meaningful benefit over semaglutide. Despite the widespread morbidity and mortality burden of HFpEF, current treatment options are limited, corresponding author Nils Krger, MD, with the division of pharmacoepidemiology and pharmacoeconomics at Brigham and Womens Hospital, said in a statement
Dysbiosis has been associated with an increased permeability of the gut barrier, a condition that allows endotoxins like LPS to enter the bloodstream, triggering an inflammatory response that can contribute to the progression of CKD (Evenepoel et al., 2023)
