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Conclusions Ischemic stroke triggers a coordinated metabolic crisis characterized by ATP depletion, mitochondrial dysfunction, excitotoxicity, oxidative and nitrosative stress, maladaptive glycolysis, lactate and pH dysregulation, NAD + /FAD imbalance, inflammatory immunometabolism, endothelial-pericyte uncoupling, and impaired neurovascular repair
We identified 48 protein spots in 2-D gel analysis and selected proteins were divided into 64% collagen components and 30% non-collagen components as shown by the MALDI-TOF analysis
Made & tested in Canada Synthesized and lyophilized domestically, then independently analyzed before it ships no imported mystery vials
The trade-off: Injections deliver the molecule most efficiently, but they dramatically raise the "risk floor" due to issues like sterility and systemic allergic responses
