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Hormonal changes including suppressed thyroid hormone (T3) and leptin levels may compound cold intolerance during prolonged restriction
Mild diarrhea can occasionally occur when starting this supplement
But again, thats to avoid a protein deficiency, which in addition to fatigue and hunger is associated with brittle hair and nails, swelling (edema), dry skin, rashes, and frequent infections
Supplementary Table 2 Correlation of changes in eGFR at week 104 with changes in body weight, blood pressure and HbA1c
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