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Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges
10.1152/ajpendo.1989.257.6.E916 Am J Physiol-Endocrinol Metab
Leonurine improves bovine oocyte maturation and subsequent embryonic development by reducing oxidative stress and improving mitochondrial function
3 These free radicals originate from everyday factors such as pollution, anxiety, and poor dietary choices
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