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Interestingly, both Nrf2 and HO1 co-localized with reactive astrocytes, the major GSH suppliers for neighboring neurons, in the degenerating spinal cord of SOD1 G93A rats, and this was interpreted as a reactive attempt to prevent cell death
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From this, we can prove that berberine not only activates GLP-1R of islet cell through the secretion of intestinal L cell, but also promotes the function of GLP-1 secretion of islet cell
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