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Through increased labeling of BCKA-derived metabolites and increases in levels of BCAA breakdown, such as glutamate, alanine, and 3-hydroxyisobutyric acid, they discovered that tirzepatide treatment stimulated catabolism of BCAAs/BCKAs in BAT

Keep using the treatment even after acne has visibly improved, to prevent new acne from forming

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These effects are primarily mediated through the suppression of pro-inflammatory cytokines (38)