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These materials are provided for laboratory investigation and scientific experimentation and are not supplied for use in humans or animals

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Hence, most of them show poor bioavailability and subpar therapeutic response

After being phosphorylated, LAT binds to Grb2, Gads, PLC-1, and the guanine exchange factors, VAV and SOS, leading to the activation of PI3K and MAPK-dependent pathways and production of inflammatory cytokines (Fig