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[9] For methylation-focused NNMT studies, stronger experimental designs may include SAM, SAH, SAM/SAH ratio, nicotinamide, 1-methylnicotinamide, NAD + , global DNA methylation, locus-specific DNA methylation, histone methylation markers, RNA expression profiling, and tissue-specific analysis where relevant
A number of functions, including nerve growth, brain function, and red blood cell production, are dependent on vitamin B12
But serious side effects like allergic reactions are rare
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