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With the increasing use of GLP-1 receptor agonists for type 2 diabetes and weight management, it is important that GPs actively address reproductive health considerations in women of child-bearing age, she told newsGP

Despite this shared mechanism, the two receptors exhibit distinct expression patterns and physiological roles that are genuinely complementary: When both axes are activated concurrently, the cAMP response in pancreatic -cells exceeds that of either agonist alone, indicating synergistic rather than merely additive intracellular signaling

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