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I lost 63 lbs over the past year, 51 of that on Tirzepatide
Do not attempt to accelerate your own titration schedule without provider approval
If you are on a 0.25mg starting dose , even minor concentration changes represent a larger percentage of your total dose compared to someone on 2.4mg
Pre-dosing with 25mg ondansetron 30 minutes before MT-2 can suppress nausea without interfering with central arousal effects, but dose reduction is the primary solution
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
