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PMC 4585313
It was originally developed as a chemically modified ligand designed to stimulate the release of growth hormone (GH) while exerting minimal influence on other endocrine axes
When digestion slows (such as on Wegovy), it can cause symptoms such as bloating, acid reflux or heartburn , and indigestion
NICE has not yet issued guidance on either agent, as appraisal processes are typically initiated only after regulatory approval, although scoping can occur earlier
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