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While the gastrointestinal side effects of GLP-1s are very common and manageable for many, between 15% and 25% of people simply can't tolerate them
Cosio FG, Hickson LJ, Griffin MD, Stegall MD, Kudva Y
* Percent Daily Reference Intakes (RI) are based on a 2,000 calorie diet
Beyond modest lipid improvements, GLP-1 receptor agonists have demonstrated substantial cardiovascular benefits in large-scale outcome trials, establishing them as important cardioprotective agents for appropriate patients
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