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Factors of glutathione deficiency include: Exposure to chemical toxins (including environmental pollution) UV radiation exposure Chronic stress Excessive alcohol use Smoking Poor diet Certain medications And we see the deficiency manifest as wrinkles, inflammation, hyperpigmentation and melasma
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Many of these areas are highlighted below in the figure adopted from Sen and Packer to illustrate these roles of glutathione and to emphasize the importance of maintaining the redox state of the cell[11]
