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Clinical Drug Research Progress for GLP1R According to incomplete statistics, there are currently 413 GLP1R-targeting drugs worldwide, with nearly 110 in preclinical stages and a total of 154 in clinical stages or already on the market
Indeed, excessive ROS disrupt the BBB integrity, impairing its selective permeability (Hu et al., 2020)
For this reason, researchers are exploring potential behavioral effects of GLP-1 medications, even though this is not their intended or approved use
Most concerning are recent case reports of drug-induced gastroparesis
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