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To combat oxidative stress, iPSCs employ a sophisticated antioxidant defense system, including superoxide dismutase and glutathione peroxidase, which are essential for protecting cells from ROS-induced damage [100]
Insert the needle through the rubber stopper of the KLOW vial at a slight angle
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The second step in BH 4 synthesis, catalyzed by 6-pyruvoyltetrahydropterin synthase (PTPS), involves the Zn 2+ and Mg 2+ -dependent rearrangement of 7,8-dihydroneopterin triphosphate, with concommitant loss of the triphosphate, to 6-pyruvoyltetrahydropterin
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