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Perivascular adipose tissue and vascular perturbation/atherosclerosis
In a large randomized trial comparing four treatment strategies in 932 couples with stage I or II endometriosis or unexplained infertility, cumulative pregnancy rates during four treatment cycles were as follows: intracervical insemination (10%), intrauterine insemination (18%), gonadotropin therapy and intracervical insemination (19%), and gonadotropin therapy and intrauterine insemination (33%) (16) , (29)
By boosting growth hormone levels, these compounds may improve slow-wave sleep, protein synthesis, and energy metabolism
UNRESOLVED QUESTIONS Despite their remarkable therapeutic potential, GLP-1-based multi-agonists raise several unresolved questions that must be addressed to ensure sustainable, equitable, and effective integration into long-term clinical care
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